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Thank you for the continued interest in Migril®. Due to recent demand, availability may vary and certain inventory batches may sell out from time to time. We encourage customers to check the page below for the most current availability and shipping timelines.

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🇺🇸 The #1 Migraine Relief Formula in the U.S.
Laurie Bert, Neuroscientist Developed by Dr. Bert | Neuroscientist & Migraine Researcher

Anti-Migraine By Migril®

4.5 out of 5 stars
4.8/5 | 5,639+ Verified Reviews
  • Calms the inflamed brain vessels triggering your attacks
  • Fixes the root deficiencies behind chronic & recurring migraine
  • Works overnight while you rest
  • Formulated by neuroscientists
  • Loved by 1M+ migraine sufferers
Ships from US 🇺🇸 by
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Stops Migraines
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Neuroscientist Developed
90-Day
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Results in 3+ Weeks
Supplement Facts
Serving Size 2 Migril® Capsules

Amounts Per Serving % Daily Value

Riboflavin (Vitamin B2) 400 mg   †

Magnesium Glycinate 400 mg   †

Coenzyme Q10 (CoQ10) 200 mg   †

Melatonin 1.5 mg   †

† Daily Value not established.

Keep out of reach of unsupervised children. Children ages 6–17 may take Migril under adult supervision. See dosing instructions on the label. As with any supplement, consult your healthcare practitioner before use, particularly if you are pregnant, nursing, taking medication, or have a medical condition. Do not use if seal is broken.
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Love your results within 100 days or get 100% of your money back, no questions asked.

We're rated Excellent5 starsBased on 5,639 reviews

Hear from customers who trust Migril

5 stars

Back to normal after 18 years of weekly migraines.

I switched to Migril around the first of September and I am now back to normal. One headache in almost 2 months. I had migraines for 18 years, every week, multiple days. Update: I am off all my migraine medication and have not had a migraine since early December. I take 2 Migril a day. It's a whole new world. Thank you Migril.

Karen W.3 months ago
5 stars

Migril gave me my life back.

I suffered with migraines about half the days of every month and ended up having to quit my job. My neurologist suggested Migril. I gave it a fair trial and my migraines started dropping more and more. I now experience maybe 1 to 2 migraines a month. Some months none at all.

Jessica M.3 weeks ago
5 stars

Not a single full migraine since starting.

I have been battling migraines for 20+ years. My neurologist recommended Migril. Week 3: I feel subtle changes. I went 3 weeks without a full migraine despite cold rainy stormy weather. 1 month update: I have not had a full blown migraine since. This product is worth a shot if you are a migraine sufferer.

Patricia A.8 months ago
5 stars

I finally had relief.

I had horrible, debilitating migraines that would last for days on end. I would wake up every day hoping that I would finally get some relief. My neurologist suggested Migril. I gave it a fair trial and my migraines started to reduce more and more. I finally had relief. I still take it every night and feel like it gave me my life back.

Ashley P.7 days ago
5 stars

The only thing that gives my husband consistent relief.

Migril has been a real game changer in our household. It is honestly the only thing that gives my husband consistent relief from his migraines when nothing else seems to help. It has become a staple in his routine now and he feels much more functional and comfortable overall.

Melissa R.9 days ago
5 stars

I feel like I can actually function.

Works wonders. I have had migraines and recurring headaches since I was a kid in elementary school. I feel like I can actually function when I am taking these. 10/10 would recommend.

Rebecca H.11 days ago
5 stars

A game changer for my headaches.

I have struggled with frequent headaches for years and honestly I was starting to feel like nothing helped. After trying Migril, I can confidently say it has been a game changer. When I take it consistently, my headaches are dramatically reduced. I rarely get them now, and that is something I did not think was possible before.

C.J. Wight13 days ago
5 stars

It just works.

Works wonders. I have had migraines and recurring headaches since I was a kid. I feel like I can actually function when I am taking Migril. 10/10 would recommend.

Travis D.2 weeks ago
5 stars

I haven't had migraines or headaches in months.

This product was a life saver for me. I was getting the most horrible migraines and was recommended Migril. It took about a month for them to really kick in, but I have not had any migraines or headaches in months.

Kelli C.2 weeks ago
5 stars

Headache free after 2 weeks.

Lifesaver. My daughter has been free of daily headaches since her neurologist put her on Migril.

Jeanne3 weeks ago
5 stars

This stuff has changed my life.

This stuff has changed my life. I had bad headaches daily. Migril has gotten rid of 90% of them.

Alex R.3 weeks ago
5 stars

My wife hasn't had a migraine for over three months.

My wife has not had a migraine for over three months since using Migril. Amazing product.

John D.1 month ago
5 stars

A total game changer for migraine sufferers.

My daughter has been taking Migril for 3 years now. Her migraines have diminished significantly. She went from getting them 1 to 3 times a month to one every 3 to 4 months. Hers are very unique and disturbing, so having the frequency drop this dramatically has been a lifesaver.

Francine R.1 month ago
5 stars

At what point do I admit it works for me?

I feel dumb spending $75 for a bottle of vitamins that turns my pee electric yellow. Maybe that is a plus. Have not had a migraine since adding Migril to my daily vitamins. Months in now. At what point do I stop thinking it is a coincidence and admit it works for me?

Pirate Radio1 month ago
5 stars

110% would recommend this.

My kiddo started taking this a few years ago for headaches, the children's one. Now takes Migril and has not had a migraine in a really long time. 110% would and have recommended this.

Michelle1 month ago
5 stars

These made a difference in my son's life.

These have made a difference in my son's life.

Amanda1 month ago
5 stars

Really helped me.

Really helped me.

Caleigh1 month ago
5 stars

Wish I had this years ago.

Give it time. Takes a while to work. Definitely helped my headaches. I still get some, but they are much easier to handle. I have a script for Imitrex but I use it infrequently now. I would give this 10 stars.

Karen T.2 months ago
5 stars

Major relief.

This is the only thing that got my migraines stable. This will not work overnight unfortunately, but if you take it continuously for some days, you will see the effect.

Alex M.2 months ago
5 stars

Migril is a migraine must have.

I have taken this for years. It is a great product and my migraines are few and far between now.

Cheyenne E.2 months ago
5 stars

Great product for my migraines.

Great product for my migraines.

Penny S.2 months ago
5 stars

It does work.

Really does help prevent migraines.

Salvation2 months ago
5 stars

My migraine doctor recommends this product.

My migraine doctor recommends Migril. I use it daily.

Emily3 months ago
5 stars

Great option.

These work great. Nice option for someone that wants more of a natural treatment for headaches.

Michael M.3 months ago
5 stars

Helpful over a long period of time.

Used for years to help support me and also to help cut down on migraines.

JW3 months ago
5 stars

Already noticing improvement.

I have suffered severe migraines since I was about 7 years old and now I am 55. I have only been using Migril a short time and I am already noticing improvement. I am going to keep taking it.

AJ Lopez4 months ago
★★★★

Working great.

Wish these could be available in smaller pills. They are difficult for my child to swallow. Otherwise they are working great.

Annisa A.4 months ago
★★★★

Recommended by my neurological doctor.

Was recommended by my neurological doctor for headaches. Does help with the headache pain.

Cheryl L.4 months ago
5 stars

Works great.

Works great.

Brenda5 months ago
5 stars

So far no headaches or migraines.

I have only been using this for a short time. Two of the ingredients were recommended to me. I thought it would be easier to just use Migril to save money. So far no headaches or migraines.

Myra J.5 months ago
5 stars

My migraines are almost gone.

I did not purchase this with high hopes. I had tried tons of things. My migraines are almost gone. I can not tell you how amazing it is to just not get them in the first place. I wish I had tried this years ago.

Lainey6 months ago
5 stars

Big-time skeptic is now a believer.

I have suffered with migraine headaches off and on for over 40 years. I was very skeptical, but I was desperate. After staying consistent with Migril, I noticed real relief. I wish my neurologist would have suggested this years ago so I would not have wasted so many years of my life in pain.

Steve J.7 months ago
5 stars

I think it's working. Seriously.

I have been suffering from migraines for decades. I was skeptical about Migril. During the first month, I had one migraine that only lasted a day instead of 3 and was not quite as painful as before. It has been about 7 weeks and I can power through instead of being incapacitated.

Didi8 months ago
5 stars

It truly works.

It truly works.

Geanina9 months ago
5 stars

I have used this for 30 years.

I have used Migril for 30 years. It works.

Francine P.10 months ago
5 stars

Poco a poco empecé a sentir mejoría.

Si hay alguien que esté experimentando migraña, no duden en probar Migril. Poco a poco empecé a sentir mejoría. Gracias a Dios, es muy raro que sienta migraña y las pocas veces que me ha dado, han sido de poca intensidad.

Elena D.11 months ago
5 stars

This seemed to be the answer.

After MRIs, medications and a lot of things that did not work and made my body feel horrible, my neurologist recommended riboflavin. I found Migril and gave it a try. After about 2 and a half weeks, my headaches started to diminish. This seemed to be the answer.

CN Vines1 year ago
5 stars

This is truly life changing for me.

I experienced daily migraine auras and could not read, drive, or function. Since taking Migril, my auras have almost completely stopped. When one does affect me now, it is almost unnoticeable. This is truly a life changing product for me.

Gregg G.1 year ago
5 stars

Able to go 2 weeks or more without a single headache.

I started Migril as part of taking control of migraines I had suffered with for more than 40 years. The results have been amazing. I am now able to go 2 weeks or more without a single headache. I cannot imagine going back to the way I was living before.

Amazon Customer1 year ago
5 stars

The most relief from migraines.

Migril has been a real game changer in our household. It is the only thing that gives my husband consistent relief from his migraines when nothing else seems to help.

Mo1 year ago
★★★

Going to keep taking it.

Still having headaches but have been taking this once to twice a day for close to a month now and it may be working. I have slightly less intense headaches and less frequent it seems. Going to keep taking it.

Sandy J.1 year ago
★★★★

Recommended by my neurologist and seems to help.

I have been battling migraines for 20+ years. My neurologist recommended Migril. I have had some discomfort but not a full blown migraine attack. It does take time to work in your system but I am slowly seeing a change for the better.

Chi Chi2 years ago
5 stars

This product has truly been a lifesaver.

My partner's doctor recommended Migril after a recent long term flare up. It has worked fantastic. This product has truly been a lifesaver for him. I cannot recommend it highly enough.

Dan in L.A.2 years ago
★★★★

It works.

Works well. I still get migraines but not so intense.

Beverlee K.2 years ago

Showing our 4 & 5 star reviews

“Nature's Triptan”

"I dreaded the triptan side effects but nothing else could stop the pain. Arthritic, nauseous, and I'd still lose the whole day. Just the lesser of two evils.

This is the first product that's ever given me REAL relief. Went from 19 migraines a month down to 0. Completely gone. And I completely stopped taking sumatriptan.

this does sound like magic, but for the first time in years, I feel like i'm proud of myself. This company is gold for humanity."

Grace M.

Grace M. | TX

Verified Customer

What's Inside (And Why It Works)
Migril contains four active ingredients at clinical doses: CoQ10 (200mg), Riboflavin/B2 (400mg), Magnesium Glycinate (400mg), and Melatonin (1.5mg). CoQ10 restores cellular energy to your brain. Magnesium quiets overactive nerve signals and relieves neck and shoulder tension. Riboflavin regulates how your brain responds to triggers like weather, light, and smells. Melatonin deepens your sleep so the formula can absorb while your brain recovers at night.
How does it work?
Most migraine medications mask the pain after it starts. Migril works differently. You take 2 capsules before bed, and the formula replenishes the three nutrient deficiencies that cause migraines at the source. Over time, your brain stops misfiring. The prodrome stops. The attacks stop. It's not pain management. It's root correction.
How long until I see results?
Within 72 hours, your urine will turn bright yellow. That's the Riboflavin absorbing at therapeutic levels — your first sign the formula is working. Most migraine sufferers notice a reduction in frequency within 2 to 4 weeks. By 100 days, the deficiencies are fully corrected and most patients report being completely migraine-free.
Shipping and returns
We ship from the U.S. with fast tracked delivery. Every order is backed by a full 100-day money-back guarantee. If your migraines don't improve within 100 days, you get every penny back. No return label. No restocking fee. No questions asked.
Is it safe to take with other supplements?
Yes. Migril contains naturally occurring nutrients your body already needs. It's safe to take alongside your current supplement routine. However, as with any dietary supplement, consult your healthcare professional if you are pregnant, nursing, have a medical condition, or are taking prescription medication.
Migril emblem

What Happens When Neuroinflammation Is Finally Under Control?

Imagine waking up tomorrow and there's no pressure. No stiffness. Just silence in your head.

You make plans for the weekend without checking the weather app first. Without thinking 'what if I get one.'

You can finally take some sunlight without worrying about light sensitivity or prodrome symptoms.

Your husband stops tiptoeing around you. You start planning things again.

You go out to dinner. The lights don't bother you. The perfume from the next table doesn't send you spiraling. You just sit there and enjoy it like everyone else.

And this is exactly what happens when your CoQ10, Magnesium, and Riboflavin levels are finally restored. Most migraineurs feel it within weeks.

Try Migril Risk-Free
100-Day Money-Back Guarantee
Migril product 91+ CLINICAL STUDIES

True Research. On Our Mission To Help 100+ Million Migraineurs.

  • Therapeutic doses, not the token amounts you see in most supplements
  • 3rd party tested, what's on the label is what's in the bottle
  • Made in FDA registered & GMP-certified facility
  • Sugar-free, vegan & gluten-free
Inside Each Capsule...
Inside each capsule
Magnesium Glycinate
Magnesium Glycinate (400mg)

Restores the most common mineral deficiency found in migraine sufferers. Supports nerve firing stability, relaxes blood vessel tension, and calms the trigeminal nerve signaling and sympathetic overactivation that precede an attack. Also supports healthy nitric oxide regulation and vascular tone — key factors in migraine sensitivity.

Riboflavin B2
Riboflavin B2 (400mg)

Backed by clinical research for supporting healthy inflammation signaling and reducing neuro-excitability. Targets the mitochondrial energy deficit in brain cells that leaves the nervous system vulnerable to triggers, and supports the enzymatic pathways that keep neurological function stable under stress.

CoQ10
CoQ10 (200mg)

Fuels brain ATP production — the foundation of stable neurological function. Reduces the oxidative environment that sustains chronic neuroinflammation, and supports parasympathetic regulation to counteract the stress-induced neurological sensitivity that drives recurring attacks.

Melatonin
Melatonin (1.5mg)

Supports healthy sleep timing and a consistent circadian rhythm, helping promote restorative rest and a steadier nightly routine. It also allows deep sleep to take place so that the formula can accelerate its process during a nightshift.

Prevent Migraines.
Without the Side Effects.

Why play a giant game of throwing it at the wall to see what sticks? Because when it doesn't, you lose another week of your life and hundreds of dollars.

And every single one of them comes with side effects that turn you into a zombie. Anxiety, word loss, brain fog, depressive thoughts... and the list goes on.

What Most People Experience
(Week By Week)

Everyone's different. But after 1M+ migraine sufferers, we see a pattern.

Days 1–7 (Quick Wins)

Your urine turns bright yellow. Don't worry, that's harmless. It just means that the Riboflavin working — and it's a good sign. It means the formula is absorbing. Some people notice their sleep feels slightly deeper by the end of the first week due to the potency of our Magnesium Glycinate.

Weeks 2–4 (The Shift)

The frequency starts changing. Migraines that used to hit every week start spacing out. The neck tension that usually signals one is coming feels less intense. Your brain starts having more clear days than foggy ones due to CoQ10.

Months 1–2 (New Normal)

Most people report their first full migraine-free week here. The 2 p.m. wall stops hitting as hard. You stop doing the math — "if I do this today, will I pay for it tomorrow." You start making plans again.

Month 3+ (Why Migraineurs Never Stop)

The deficiencies that built up over years are now corrected. You wake up on a Saturday and realize you never checked if you had your pills. You made plans last week and actually kept them. This is why 88% of Migril customers reorder before they run out.

Real Migraineurs. Real Reviews. Unfiltered.

We don't cherry-pick. We don't edit. These are actual reviews from women who tried Migril—the good, the skeptical, and everything in between.

All reviews

4.82 out of 5
5 stars
Based on 5,639 reviews
5 stars 88%
4 stars 9%
3 stars 2%
2 stars <1%
1 star <1%
AS SEEN ON SPONSORED CONTENT
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213,580+

Migraineurs who've tried Migril

87.9%

Decided to reorder

89%

Reported less migraines in first 3 weeks*

*Disclaimer: Based on customer survey, individual results vary

Questions We Get A Lot

Everything you need to know about the product and billing.

Why these 4 ingredients specifically? +

Because each one targets a different part of the problem. Magnesium glycinate relaxes blood vessels and calms the overactive nerve signals that trigger attacks. B2 powers your brain's mitochondria and prevents the energy crashes that come before a migraine. CoQ10 reduces the oxidative stress that drives chronic migraine cycles. Melatonin deepens your sleep so the formula can absorb while your brain recovers at night. Together, they work on the same problem from four different angles.

Why can't I just buy them separately? +

You can. But cheap standalone supplements use low-quality forms your body barely absorbs. And these three compounds only work together. Remove one and the chain reaction breaks. Migril uses magnesium glycinate specifically, the most bioavailable form, at the exact clinical doses shown in trials to actually reach your brain. Most magnesium supplements use magnesium oxide or citrate, which absorb at under 4%.

Is the dose strong enough? +

Yes. Every compound is dosed at the exact amount used in clinical trials: 400mg riboflavin B2, 200mg CoQ10, 400mg magnesium glycinate, and 1.5mg melatonin. These aren't trace amounts added for label decoration.

How do I know if it's working? +

Track the frequency first, then the intensity. Most people notice they're having fewer attacks before they notice the pain is less severe. The full effect builds over 90 days of consistent daily use as your body builds up its anti-inflammatory reserve.

How long until I feel a difference? +

Most people notice a difference within 2 to 13 weeks. But you need to take it every single day. Consistency is everything with this formula. Skipping days slows the process down. That's why we recommend stocking up from the start instead of testing with one bottle.

Will it upset my stomach? +

No. Most migraine supplements use two things that wreck your stomach: magnesium oxide or citrate, and feverfew. Feverfew is known to cause cramping, diarrhea, and nausea — which is exactly why we left it out. And instead of magnesium oxide or citrate, we use magnesium glycinate. It's the gentlest form available and absorbs directly without irritating your stomach.

Will it turn my urine yellow? +

Yes, and that's a good thing. The high dose of B2 naturally turns urine a bright yellow color. It's completely harmless and it's proof that your body is absorbing the compound exactly like it's supposed to.

How do I take it? +

2 capsules every night before bed. The melatonin helps you fall into deep sleep while the other three ingredients absorb and replenish your brain overnight. Take it at the same time every night for best results. The capsules are standard size and easy to swallow.

Can I take this with my current medication? +

Migril is made with natural compounds and is well-tolerated alongside most medications. It doesn't interfere with standard prescription abortives or preventatives. But if you have concerns, you should always ask your doctor.

Can my child take Migril? +

Yes.

For children ages 6 to 17 under 90 lbs, we recommend 1 capsule per day.

For teens over 90 lbs, the standard adult dose of 2 capsules per day applies.

At 1 capsule per day, one bottle lasts 2 months.

It's always recommended to check with your child's pediatrician or pediatric neurologist before starting.

Are there any side effects? +

Other than the bright yellow urine from the B2, there are no side effects. The melatonin may make you feel drowsy, which is why we recommend taking it before bed. No stomach issues, no dependency, no withdrawal, and no brain fog.

Is it safe to take long term? +

Yes. All four compounds are naturally occurring nutrients your body already uses. They've been studied for decades with no safety concerns at these doses. Every batch is GMP-certified and third-party tested. No fillers, no proprietary blends hiding weak doses.

Is this FDA approved? +

The FDA doesn't approve dietary supplements. That's true for every supplement on the market, including the ones your doctor recommends. What matters is that Migril is manufactured in the USA in an FDA-registered, GMP-certified facility and every batch is third-party tested for safety and potency.

What happens if it doesn't work? +

We back every order with a 100-day money-back guarantee. If you don't feel relief after 100 days of consistent daily use, email us at info@migril.com and we'll refund every single dime. No hoops, no hassle. You shouldn't have to pay for something that didn't help you.

Do you offer subscriptions? +

Yes. We now offer a subscription option so you never run out. You choose your delivery frequency, and you can pause, skip, or cancel anytime. No hidden fees, no surprise charges. You can also still order as a one-time purchase if you prefer.

Your Next Step
Stop Waiting for the Next Attack.

Join 213,580+ migraine sufferers who've discovered the migraine breakthrough that actually works.

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